African Journal of Biological, Chemical and Physical Sciences 2023-11-07T11:29:42+00:00 Dr. David Azanu Open Journal Systems <p><strong>African Journal of Biological, Chemical and Physical Sciences (AJBCPS)</strong> - <strong>ISSN: </strong>2790-9522 (Print) | 2790-9530 (Online) is an interdisciplinary and quality peer-reviewed open-access journal. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of physics, chemistry, and biology. All manuscripts must be prepared in English and are subject to a rigorous and fair peer-review process.</p> <p>AJBCPS publishes annually but articles can be submitted and published any time of the year as soon as article is ready.</p> Medicinal uses, phytochemistry and pharmacological activities of cleome species (Cleomaceae): A review 2023-07-07T09:20:19+00:00 Nkiruka Theresa Nnadozie Oluremi Adeniran Samuel Okhale <p>This study is reviewing the medicinal uses, phytochemistry and pharmacological activities of cleome species. Ethanomedically, cleome species have used to treat a variety of diseases such as fever, flu, headaches, coughs, snakebites, nephritis, inflammation, bronchitis, diarrhoea, skin conditions, liver disorders and malarial fever symptoms. This study reviewed the previous phytochemical analysis of this plant species, its bioactive flavonoids and terpenoids, tannins, alkaloids, anthraquinones and saponins which showed to be found in the various extracts of the plant. These bioactive compounds and extracts all showed antioxidant, anti-malarial, anti-cancer, antibacterial, and hepatoprotective effect. The enormous range of medicinal applications described thus far cannot be exaggerated, despite the fact that just a few species in this genus have been studied. Given their pharmacological properties, this plant species shows potential for further analytical studies and subsequent clinical trials to advance the plants' therapeutic potential.</p> 2023-11-07T00:00:00+00:00 Copyright (c) 2023 Nkiruka Theresa Nnadozie, Oluremi Adeniran, Samuel Okhale Evaluation of the total phenolic, total flavonoid, and radical scavenging properties of the stem bark and leaves of Pterocarpus osun 2023-11-07T11:29:42+00:00 Adewale Elijah Fadeyi Oluremi Isola Adeniran <p>Introduction: Medicinal plants have the capacity to scavenge free radicals due to their potential to stabilize harmful molecules, which contributes to oxidative stress that results in non-communicable diseases like cancer, diabetes. Methodology: Folin-Ciocalteu colorimetric method and the aluminium chloride method respectively, were used to evaluate the total contents of phenolic and flavonoid of the Pterocarpus osun leaf and stem bark extracts.&nbsp; Purpose of study: The goal of the current investigation was to evaluate the total content of flavonoid, and total content of phenol present in methanol extracts of the leaf and stem bark of P. osun. Using the DPPH assay to measure the extracts' capacity to scavenge free radicals, inhibition concentrations of 0.0625, 0.125, 0.250, 0.500, and 1.00 mg/mL were noted. Results: The IC50s for the stem bark and the leaf extracts are 3.44, and 48.14 mg/mL, respectively. The amount of flavonoid in the stem bark was 2.32, and 1.50 mg quercetin/g extract for the leaf. The total phenolic content was 8.61 and, 6.61 mg gallic acid equivalent (GAE)/g extract for the stem bark and for the leaf, respectively. Conclusion: The results show that there is a correlation between radical scavenging properties and poly phenolics.</p> 2023-11-07T00:00:00+00:00 Copyright (c) 2023 Adewale Elijah Fadeyi, Oluremi Isola Adeniran